Postdoctoral opportunity at the Bermuda Institute of Ocean Science
A postdoctoral position is available in the lab of Julius Barsi at the Bermuda Institute of Ocean Sciences. Work in the Barsi lab aims to explain the mechanism by which genomic information is translated into anatomical structure and by extension, make the consequence of genetic perturbation explicit. Of equal interest, is a desire to interrogate the ocean environment and create nature- inspired solutions to help address global health challenges.
At present, we intend to survey genes that encode gas vesicles (GVs) in the Sargasso Sea. These sub-cellular structures are common in some bacteria, as well as Archaea. They are believed to serve as a mechanism by which unicellular organisms position themselves along the water column. Irrespective of their biological function in nature, GVs are endowed with particularly interesting properties that could potentially transform biomedical imaging.
We are now seeking a postdoctoral candidate to help develop a PCR-based assay for GV gene cluster discovery. This unique opportunity will combine: (a) field work with small research vessels, (b) primer-design and evaluation of multiplex PCR assays, (c) in- house Oxford Nanopore Sequencing, and (d) bioinformatic analysis.
The following two papers provide relevant context. The first, concerns the organelle of interest and the second, serves to illustrate the depth of molecular biology typically employed in Dr. Barsi’s research:
1. Huber et. al. (2023) “Cryo-EM structure of gas vesicles for buoyancy-controlled motility.” Cell. 2023 Mar 2;186(5):975-986
2. Barsi & Davidson (2016) “cis-Regulatory control of the initial neurogenic pattern of onecut gene expression in the sea urchin embryo.” Dev Biol. 2016 Jan 1;409(1):310-318
Candidates. Applications are encouraged from talented and motivated individuals who have a Ph.D. or are nearing completion of their Ph.D. with experience in molecular biology, bioinformatics, multiplex PCR-assay design, and Oxford Nanopore Sequencing. Interest or experience in field work enabled by small research vessels is desirable. Top candidates will have a solid record of research productivity, first-rate communication skills, enthusiasm for basic research and above all, independence. Candidates should send a cover letter, a detailed curriculum vitae, and names and contact details for three references to julius.barsi@bios.edu
Start Date and Project Duration. The ideal start date would be ASAP 2023. The position is funded for one year, with the potential for continuation depending on job performance and the ability to attract additional research funds.
The Bermuda Institute of Ocean Sciences (BIOS) is an independent US non-profit scientific research and educational organization based in Bermuda. For over 120 years BIOS-based researchers and visiting scientists have worked to explore the ocean and address critical local and global environmental issues. In 2021, BIOS merged with the Julie Ann Wrigley Global Futures Laboratory at Arizona State University, joining its mission to help ensure a habitable planet and a future in which well-being is attainable.
Compensation - The salary will be in the range of $52K-$62K. The salary of the finalist(s) selected for this role is set based on a variety of factors, including but not limited to, experience, qualifications, skills, education, specialty, training, and internal equity. BIOS is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin, disability status, protected veteran status, or any other characteristic protected by law.
Given the restrictions on sponsored dependents residing in Bermuda set by the Department of Immigration, all applicants are recommended to review Section 5 of the Work Permit Policy. Review of applications will commence immediately.
http://www.bios.edu/currents/medical-imaging-and-marine-bacteria/
http://www.bios.edu/currents/scientist-at-work-a-conversation-with-julius-barsi/
New state-of-the-art microscopes and related components just arrived from USA, Germany, and Japan !
They are part of a larger suite of precision instruments that together will form the Barsi Lab’s transgenic facility.
This system allows us to deliver genetically engineered DNA into a variety of organisms and manipulate their genome.
